Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296251 | 0.86 | OPRM1 (0.53) | MEN1HTTKMT2ASLC6A4 | |
| SCHEMBL8297198 | 0.84 | HSD11B1 (0.53) | MEN1HTTKMT2A | |
| SCHEMBL7843683 | 0.83 | HTR1D (0.55) | — | |
| SCHEMBL7848593 | 0.83 | SLC6A4 (0.49) | SLC6A4MAPK1 | |
| SCHEMBL8296229 | 0.81 | DRD2 (0.54) | MEN1HTTKMT2ASLC6A4 | |
| SCHEMBL8299590 | 0.78 | DRD2 (0.51) | MEN1HTTKMT2ASLC6A4 | |
| SCHEMBL7845970 | 0.76 | KMT2A (0.58) | MEN1HTTKMT2A | |
| SCHEMBL5727535 | 0.74 | SLC6A4 (0.63) | SLC6A4MAPK1 | |
| SCHEMBL8298661 | 0.73 | MEN1 (0.50) | MEN1HTTKMT2ASLC6A4 | |
| SCHEMBL13499597 | 0.73 | SLC6A4 (0.69) | SLC6A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076658-A1 | SEROTONERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-21 | — | — | EP | claimed |
| WO-1999055697-A1 | SEROTONERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-04 | — | — | WO | claimed |