Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299871 | 0.86 | HTR1A (0.57) | HTR1DHTR1A | |
| SCHEMBL7843427 | 0.83 | MEN1 (0.52) | — | |
| SCHEMBL8301940 | 0.80 | DRD2 (0.61) | HTR1DHTR1BHTR1A | |
| SCHEMBL13499597 | 0.77 | SLC6A4 (0.69) | HTR1A | |
| SCHEMBL7213780 | 0.75 | HTR1A (0.69) | HTR1A | |
| SCHEMBL7847632 | 0.74 | HTR1A (0.57) | HTR1BHTR1A | |
| SCHEMBL27510233 | 0.74 | ADRA1D (0.52) | HTR1DHTR1BHTR1A | |
| SCHEMBL28718864 | 0.74 | HTR1A (0.65) | HTR1A | |
| SCHEMBL29535423 | 0.74 | HTR1A (0.65) | HTR1A | |
| SCHEMBL28718866 | 0.73 | HTR1A (0.75) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076658-A1 | SEROTONERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-21 | — | — | EP | claimed |
| WO-1999055697-A1 | SEROTONERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-04 | — | — | WO | claimed |