Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931643 | 0.87 | MBTD1 (0.57) | MBTD1L3MBTL3L3MBTL1GFERNOTUM | |
| Hydrochloric Acid SCHEMBL17927700 | 0.85 | MBTD1 (0.55) | MBTD1L3MBTL3L3MBTL1GFERNOTUM | |
| Hydrochloric Acid SCHEMBL17748967 | 0.85 | MBTD1 (0.55) | MBTD1L3MBTL3L3MBTL1GFERNOTUM | |
| SCHEMBL532107 | 0.85 | LMNA (0.52) | GRIN2BHTR3EHTR3BHTR3AHTR3D | |
| Ethylene SCHEMBL3717036 | 0.81 | LMNA (0.48) | GRIN2BHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14275856 | 0.80 | L3MBTL1 (0.55) | MBTD1L3MBTL3L3MBTL1GFERNOTUM | |
| SCHEMBL3185733 | 0.78 | HSD17B10 (0.46) | MBTD1L3MBTL3L3MBTL1HTR3EHTR3B | |
| SCHEMBL7845356 | 0.76 | ALDH1A1 (0.45) | MBTD1L3MBTL3L3MBTL1ALOX15 | |
| SCHEMBL11387902 | 0.76 | L3MBTL1 (0.42) | MBTD1L3MBTL3L3MBTL1GFERVCP | |
| SCHEMBL314421 | 0.76 | NOTUM (0.55) | MBTD1L3MBTL3L3MBTL1GFERNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944388-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0944388-A2 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1997038665-A2 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | disclosed |