Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532107 | 0.96 | LMNA (0.52) | LMNAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL3185733 | 0.88 | HSD17B10 (0.46) | LMNAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL1953072 | 0.83 | MEN1 (0.45) | LMNAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL7845352 | 0.81 | MBTD1 (0.46) | LMNAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL14117666 | 0.79 | LTA4H (0.62) | LMNAHSD17B10MEN1KMT2ANPC1 | |
| SCHEMBL27369297 | 0.78 | PTGS2 (0.42) | LMNAALOX15HSD17B10MEN1KMT2A | |
| Tert-Butyl Formate SCHEMBL28780380 | 0.77 | GPR119 (0.42) | LMNAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL532702 | 0.77 | LMNA (0.52) | LMNAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL576814 | 0.75 | LMNA (0.67) | LMNAHTR3EHTR3BADRB1HTR3A | |
| SCHEMBL385012 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |