Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 14/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576010 | 0.76 | LMNA (0.50) | FFAR3KDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL8654462 | 0.75 | ALDH1A1 (0.49) | HSD17B10TP53ALDH1A1HPGDTSHR | |
| SCHEMBL8654643 | 0.75 | ALDH1A1 (0.49) | HSD17B10TP53ALDH1A1HPGDTSHR | |
| SCHEMBL8653231 | 0.75 | ALDH1A1 (0.49) | HSD17B10TP53ALDH1A1HPGDTSHR | |
| SCHEMBL8652188 | 0.71 | ALDH1A1 (0.51) | FFAR3KDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL7854160 | 0.70 | FFAR3 (0.46) | FFAR3KDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL11313635 | 0.68 | FFAR3 (0.46) | FFAR3KDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL5816251 | 0.68 | KDM4E (0.57) | FFAR3KDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL5814814 | 0.68 | KDM4E (0.60) | FFAR3KDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL7379538 | 0.67 | SMN1; SMN2 (0.56) | HSD17B10TP53ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665834-B1 | QUINOLONE AND ACRIDINONE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | ASTRAZENECA AB (SE) | 2001-05-30 | — | — | EP | disclosed |
| US-5622964-A | ADMINISTERING 4,6,7,8-TETRAHYDRO-5(1H)-QUINOLONE DERIVATIVE TO TREAT ASTHMA IN MAMMALS | ZENECA LIMITED (GB) | 1997-04-22 | — | — | US | disclosed |
| US-5455253-A | For urinary incontinence | ZENECA LIMITED (GB) | 1995-10-03 | — | — | US | disclosed |
| EP-0665834-A1 | QUINOLONE AND ACRIDINONE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994008966-A1 | QUINOLONE AND ACRIDINONE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1994-04-28 | — | — | WO | disclosed |