Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033504 | 0.84 | FFAR3 (0.39) | FFAR3GAAALDH1A1HPGDKDM4E | |
| SCHEMBL11031879 | 0.82 | FFAR3 (0.47) | FFAR3GAAALDH1A1HPGDKDM4E | |
| SCHEMBL11032599 | 0.81 | FFAR3 (0.47) | FFAR3ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL7148358 | 0.76 | ALDH1A1 (0.58) | GAAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11256668 | 0.75 | ALDH1A1 (0.57) | GAAALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL7107070 | 0.72 | LMNA (0.69) | GAAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL5816251 | 0.71 | KDM4E (0.57) | FFAR3GAAALDH1A1HPGDKDM4E | |
| SCHEMBL7845674 | 0.68 | FFAR3 (0.64) | FFAR3ALDH1A1HPGDKDM4ETP53 | |
| SCHEMBL9831538 | 0.68 | LMNA (0.71) | GAAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11292115 | 0.66 | TSHR (0.74) | FFAR3GAAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059291-A1 | Antihypertensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-08 | — | — | EP | claimed |