SCHEMBL78465

SCHEMBL78465

Nc1ccc(N2CCCC2=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
HPGD P15428 6/20 0.56
AKR1C3 P42330 5/20 0.56
DDB1 Q16531 1/20 0.52
CRBN Q96SW2 1/20 0.52
NPC1 O15118 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
TP53 P04637 2/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
RAB9A P51151 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85175 0.94 ALDH1A1 (0.58) ALDH1A1HPGDAKR1C3DDB1CRBN
SCHEMBL85591 0.92 ALDH1A1 (0.57) ALDH1A1HPGDAKR1C3DDB1CRBN
SCHEMBL11142367 0.91 ALDH1A1 (0.74) ALDH1A1HPGDAKR1C3NPC1SMN1; SMN2
SCHEMBL11936018 0.82 USP2 (0.52) ALDH1A1HPGDSMN1; SMN2TSHRL3MBTL1
SCHEMBL1656668 0.82 ALDH1A1 (0.68) ALDH1A1HPGDAKR1C3NPC1SMN1; SMN2
SCHEMBL1171241 0.82 ALDH1A1 (0.62) ALDH1A1HPGDAKR1C3NPC1SMN1; SMN2
SCHEMBL19356857 0.82 ALDH1A1 (0.62) ALDH1A1HPGDAKR1C3NPC1SMN1; SMN2
SCHEMBL624432 0.82 ALDH1A1 (0.62) ALDH1A1HPGDAKR1C3NPC1SMN1; SMN2
SCHEMBL1507158 0.82 ALDH1A1 (0.62) ALDH1A1HPGDAKR1C3NPC1SMN1; SMN2
SCHEMBL171739 0.82 ALDH1A1 (0.62) ALDH1A1HPGDAKR1C3SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117721634-A Amphiphilic functionalized graphene fiber and preparation method thereof 兰州东立龙信息技术有限公司 2024-03-19 CN claimed
CN-112976746-B Polyester film for antistatic dry film resist and preparation method thereof 富维薄膜(山东)有限公司 2023-05-26 CN claimed
CN-116096194-A Novel method for preparing large-area perovskite film and application 合肥市旭熠科技有限公司 2023-05-09 CN claimed
CN-112976746-A Polyester film for antistatic dry film resist and preparation method thereof 富维薄膜(山东)有限公司 2021-06-18 CN claimed
CN-108587111-B Composite efficient antistatic agent for plastics 湖南辰砾新材料有限公司 2021-04-30 CN claimed
CN-111892806-A Preparation method of composite efficient antistatic agent for plastics 湖南辰砾新材料有限公司 2020-11-06 CN claimed
CN-108587111-A Composite efficient antistatic agent for plastics 湖南辰砾新材料有限公司 2018-09-28 CN claimed
EP-1628972-B1 INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI AVENTIS DEUTSCHLAND (DE) 2009-04-22 EP claimed
US-7365088-B2 Indazole-derivatives as factor Xa inhibitors SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-04-29 US claimed
US-20060135589-A1 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors ASTEX TECHNOLOGY, INC. (GB) 2006-06-22 US claimed
EP-1628972-A1 INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS Sanofi-Aventis Deutschland GmbH (DE) 2006-03-01 EP claimed
US-20040235824-A1 Indazole-derivatives as factor Xa inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-11-25 US claimed
WO-2004101556-A1 INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-11-25 WO claimed
EP-1479675-A1 Indazole-derivatives as factor Xa inhibitors Aventis Pharma Deutschland GmbH (DE) 2004-11-24 EP claimed
US-20260125357-A1 LACTATE ENHANCING COMPOUNDS AND USES THEREOF GLIAPHARM SA (CH) 2026-05-07 US disclosed
EP-4598533-A1 LACTATE ENHANCING COMPOUNDS AND USES THEREOF Gliapharm SA (CH) 2025-08-13 EP disclosed
CN-120035439-A Lactic acid enhancing compounds and uses thereof 格莱制药股份有限公司 2025-05-23 CN disclosed
WO-1997038095-A1 COMPLEX SUPEROXIDE DISMUTASE PRODUCT COLETICA (FR) 1997-10-16 WO disclosed
US-4211835-A TETRAZOLIUM COMPOUND, BLACK AND WHITE, HIGH CONTRAST KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-07-08 US disclosed
US-3980677-A Anthraquinone dyestuffs containing sulphonic acid groups BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125357-A1 LACTATE ENHANCING COMPOUNDS AND USES THEREOF LDHA, PC, LDHB ALDH1A1 405/4885HPGD 498/4885AKR1C3 78/4885
US-20040235824-A1 Indazole-derivatives as factor Xa inhibitors F11, F12, F5 ALDH1A1 1259/4885HPGD 678/4885AKR1C3 887/4885
US-20060135589-A1 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors CCNC, CDK1, CDK7 ALDH1A1 4215/4885HPGD 1261/4885AKR1C3 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.