Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845907 | 0.89 | MAPT (0.36) | HPDALDH1A1SMN1; SMN2LIPGP2RX3 | |
| SCHEMBL7836190 | 0.89 | MAPT (0.36) | HPDALDH1A1SMN1; SMN2P2RX3MAPT | |
| SCHEMBL7837543 | 0.87 | GRIN1 (0.43) | CYP3A4TLR7POLBMEN1KMT2A | |
| SCHEMBL7848694 | 0.87 | LMNA (0.41) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL7847168 | 0.87 | MTNR1A (0.49) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL8389088 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPTLIPE | |
| SCHEMBL7846719 | 0.85 | TYMS (0.41) | ALDH1A1KDM4EP2RX3 | |
| SCHEMBL7848710 | 0.85 | MTNR1A (0.37) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL7836192 | 0.84 | KDM5B (0.32) | ALDH1A1TLR7P2RX3POLB | |
| SCHEMBL7845796 | 0.84 | GRIN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |