Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 5/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352234 | 0.76 | PNP (0.60) | XDHFGFR1FGFR2 | |
| SCHEMBL24603099 | 0.76 | XDH (0.56) | XDHTYMSFGFR1FGFR2QTRT1 | |
| SCHEMBL22967337 | 0.74 | TYMS (0.59) | TYMS | |
| SCHEMBL18520454 | 0.74 | DYRK1A (0.47) | ALDH1A1TYMSDYRK1A | |
| SCHEMBL20911745 | 0.73 | NPC1 (0.54) | ALDH1A1FGFR1DYRK1ALRRK2PARP1 | |
| SCHEMBL12884842 | 0.72 | TYMS (0.46) | ALDH1A1TYMSDYRK1A | |
| SCHEMBL12820951 | 0.72 | DYRK1A (0.46) | TYMSDYRK1A | |
| SCHEMBL15061831 | 0.72 | TYMS (0.48) | ALDH1A1TYMSDYRK1A | |
| SCHEMBL24704369 | 0.72 | DYRK1A (0.46) | ALDH1A1TYMSDYRK1A | |
| SCHEMBL22227944 | 0.72 | TYMS (0.50) | TYMSDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105396-A1 | PROCESS FOR THE PREPARATION OF PYRROLO[2,3-D]PYRIMIDINES | The Trustees of Princeton University (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6066732-A | Process for the preparation of pyrrolo[2,3-d]pyrimidines | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |
| WO-2000011004-A1 | PROCESS FOR THE PREPARATION OF PYRROLO[2,3-D]PYRIMIDINES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2000-03-02 | — | — | WO | disclosed |