Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086546 | 0.92 | TPH1 (0.34) | HPGDTSHRMAPT | |
| SCHEMBL6087279 | 0.89 | ALDH1A1 (0.33) | HPGDTSHRMAPTMAPK1 | |
| SCHEMBL6085643 | 0.87 | GRIN1 (0.36) | — | |
| SCHEMBL6086605 | 0.86 | HPGD (0.42) | HPGDTSHRMAPT | |
| SCHEMBL6086149 | 0.85 | MTNR1A (0.35) | HPGDTSHRMAPTMAPK1 | |
| SCHEMBL6085665 | 0.84 | TSHR (0.34) | HPGDTSHRMAPT | |
| SCHEMBL7837061 | 0.84 | TPH1 (0.30) | HPGDTSHR | |
| SCHEMBL6088055 | 0.83 | TYMS (0.38) | TYMSHPGDTSHRL3MBTL1MAPT | |
| SCHEMBL7848879 | 0.82 | TYMS (0.35) | TYMS | |
| SCHEMBL7855251 | 0.82 | NR3C1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |