Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 4/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310547 | 0.68 | GLP1R (0.64) | GLP1R | |
| SCHEMBL6310266 | 0.67 | GLP1R (0.41) | GLP1RPGK1 | |
| SCHEMBL6303710 | 0.61 | GLP1R (1.00) | GLP1R | |
| SCHEMBL12124147 | 0.58 | MAPK13 (0.53) | GLP1R | |
| SCHEMBL10411575 | 0.57 | ALDH1A1 (0.38) | ADORA1 | |
| SCHEMBL10410234 | 0.57 | CDK1 (0.45) | POLB | |
| SCHEMBL11270290 | 0.55 | PTGS2 (0.39) | GLP1RMAPT | |
| 2,3-Dihydroxy-6,7-Dichloroquinoxaline SCHEMBL1259521 | 0.55 | MMP1 (0.50) | GLP1RPGK1 | |
| SCHEMBL1259520 | 0.55 | HRH4 (0.52) | GLP1RMAPT | |
| SCHEMBL6306880 | 0.55 | GLP1R (0.53) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |