Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859201 | 0.96 | POLB (0.41) | POLBMMP8MLYCDCHRNB2CHRNB4 | |
| SCHEMBL7857950 | 0.91 | RAB9A (0.38) | POLBMMP8KMT2AOPRK1MMP1 | |
| SCHEMBL7859250 | 0.91 | PLAAT3 (0.38) | POLBMMP8OPRK1MMP1MMP3 | |
| SCHEMBL7857056 | 0.90 | POLB (0.34) | POLBOPRK1MMP1MMP3MMP9 | |
| SCHEMBL7859124 | 0.80 | MMP2 (0.37) | — | |
| SCHEMBL7859114 | 0.77 | POLB (0.40) | POLBMMP8MLYCDCHRNB2CHRNB4 | |
| SCHEMBL7850354 | 0.77 | MC4R (0.47) | MMP8MMP9 | |
| SCHEMBL8175675 | 0.77 | OPRM1 (0.34) | POLBKMT2AOPRK1LMNA | |
| SCHEMBL7857961 | 0.76 | POLB (0.42) | POLBMMP8MLYCDCYP2D6CYP2C9 | |
| SCHEMBL7857902 | 0.76 | MLYCD (0.43) | POLBMMP8MLYCDCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |