SCHEMBL785094

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31010287	0.78	HRH3 (0.54)	DRD2SIGMAR1LMNAPARGVHL
	SCHEMBL26952641	0.76	DRD2 (0.45)	DRD2SIGMAR1LMNAPARGMEN1
	SCHEMBL18942317	0.76	LMNA (0.53)	DRD2SIGMAR1LMNAPARGTHRB
	SCHEMBL4314062	0.75	DRD2 (0.44)	DRD2SIGMAR1LMNAVHLTHRB
	SCHEMBL12112155	0.75	LTA4H (0.45)	LMNAPARGTHRBMEN1KMT2A
	SCHEMBL15014589	0.73	DRD2 (0.37)	DRD2SIGMAR1LMNAVHLCHRNB2
	SCHEMBL23775544	0.73	DRD2 (0.43)	DRD2SIGMAR1LMNAPARGCHRNB2
	SCHEMBL12424948	0.72	DRD2 (0.36)	DRD2SIGMAR1LMNAVHLCHRNB2
	SCHEMBL12384701	0.71	DRD2 (0.37)	DRD2SIGMAR1VHLCHRNB2CHRNB4
	SCHEMBL4623779	0.70	CXCR3 (0.59)	SIGMAR1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.