Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD2 | Q9BYW2 | 5/20 | 0.38 |
| ▸ | F10 | P00742 | 10/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785624 | 0.88 | F10 (0.38) | SETD2F10SLC2A1NPY5R | |
| SCHEMBL784827 | 0.87 | ROCK2 (0.37) | F10NPY5RALDH1A1ALOX15 | |
| SCHEMBL785900 | 0.87 | CTSS (0.40) | SETD2F10SLC2A1 | |
| SCHEMBL785236 | 0.85 | F10 (0.38) | SETD2F10SLC2A1NPY5R | |
| SCHEMBL784276 | 0.84 | F10 (0.39) | F10NPY5RALDH1A1ALOX15 | |
| SCHEMBL784148 | 0.83 | RORC (0.41) | F10 | |
| SCHEMBL484513 | 0.83 | CYP3A4 (0.49) | ALDH1A1 | |
| SCHEMBL785712 | 0.83 | F10 (0.37) | F10NPY5RALDH1A1ALOX15 | |
| SCHEMBL785791 | 0.83 | ALDH1A1 (0.41) | F10NPY5RALDH1A1ALOX15 | |
| SCHEMBL785090 | 0.83 | BDKRB1 (0.40) | F10ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | claimed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | claimed |
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | SETD2 2188/4885F10 524/4885SLC2A1 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.