SCHEMBL7851017

SCHEMBL7851017

O=S(=O)(Nc1c(F)cccc1F)c1nc2c(Cl)cccn2n1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACLY P53396 1/20 0.37
SLC40A1 Q9NP59 4/20 0.36
NUDT1 P36639 1/20 0.35
CYP11B2 P19099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7851696 0.83 GAA (0.45) SLC40A1
SCHEMBL10666414 0.79 ACLY (0.39) ACLYSLC40A1
SCHEMBL7851317 0.78 JAK2 (0.38) ACLYSLC40A1
SCHEMBL7842349 0.76 GAA (0.39) SLC40A1
SCHEMBL9832548 0.76 HTR6 (0.39) ACLY
SCHEMBL10660778 0.76 HPGD (0.40) ACLYSLC40A1
SCHEMBL8825630 0.75 CCR4 (0.44)
SCHEMBL7840325 0.75 CYP11B2 (0.43) NUDT1CYP11B2
SCHEMBL10397157 0.74 ACLY (0.33) ACLY
SCHEMBL8374471 0.73 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717743-B1 N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES DOW AGROSCIENCES LLC (US) 2001-11-14 EP disclosed
EP-0972774-A2 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines Dow AgroSciences LLC (US) 2000-01-19 EP disclosed
US-5571775-A EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES DOWELANCO (US) 1996-11-05 US disclosed
EP-0717743-A1 N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES DOWELANCO (US) 1996-06-26 EP disclosed
WO-1996001826-A1 N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES DOWELANCO (US) 1996-01-25 WO disclosed