Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510987 | 0.92 | LMNA (0.39) | DAGLAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7843449 | 0.87 | PDE4A (0.40) | DAGLAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7355527 | 0.83 | MEN1 (0.43) | DAGLAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7511580 | 0.81 | LMNA (0.42) | DAGLAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7383720 | 0.79 | FAAH (0.33) | GRIK1SMN1; SMN2 | |
| SCHEMBL6992446 | 0.76 | LMNA (0.38) | PDE4APDE4BPDE4CPDE4DGRIK1 | |
| SCHEMBL6995428 | 0.75 | DRD2 (0.38) | PDE4APDE4BPDE4CPDE4DGRIK1 | |
| SCHEMBL7885859 | 0.74 | RIPK2 (0.43) | PDE4APDE4BPDE4CPDE4DGRIK1 | |
| SCHEMBL6993975 | 0.74 | LMNA (0.36) | PDE4APDE4BPDE4CPDE4DGRIK1 | |
| SCHEMBL7885863 | 0.73 | MEN1 (0.42) | PDE4APDE4BPDE4CPDE4DGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107968-A2 | DIHYDRO-[1,2,3]TRIAZOLO-[4,5-D]PYRIMIDIN-7-ONE | BAYER AG (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012504-A2 | DIHYDRO-[1,2,3]TRIAZOLO-[4,5-D]PYRIMIDIN-7-ONE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-09 | — | — | WO | disclosed |