Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846211 | 0.84 | MEN1 (0.36) | MAPTTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8337012 | 0.81 | MAPT (0.35) | MAPTTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9009353 | 0.81 | USP2 (0.38) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8182725 | 0.80 | GRIN1 (0.42) | MAPTTP53KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9009363 | 0.80 | TPH1 (0.34) | MAPTTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9009425 | 0.79 | MEN1 (0.33) | MAPTTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8338415 | 0.79 | ALDH1A1 (0.45) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7848458 | 0.78 | MAPT (0.36) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7847521 | 0.78 | LMNA (0.41) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7844325 | 0.78 | TYMS (0.35) | MAPTTP53ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |