Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KYNU | Q16719 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ECE1 | P42892 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211205 | 0.88 | CTRB1 (0.50) | ELANECTRB1TP53KYNUKLK1 | |
| SCHEMBL6703656 | 0.81 | LMNA (0.60) | — | |
| SCHEMBL11255815 | 0.80 | HTT (0.56) | CTRB1ATMMMEECE1CTSL | |
| SCHEMBL6605708 | 0.79 | CTRB1 (0.52) | CTRB1TACR1ATMCTSLCTSS | |
| SCHEMBL10606513 | 0.79 | CTRB1 (0.52) | CTRB1TACR1ATMCTSLCTSS | |
| SCHEMBL21333945 | 0.78 | CTSL (0.62) | CTRB1ATMMMEECE1CTSL | |
| SCHEMBL846125 | 0.77 | CTRB1 (0.54) | ELANECTRB1KYNUKLK1TACR1 | |
| SCHEMBL11567174 | 0.77 | ELANE (0.60) | ELANECTRB1KYNUPRTN3ATM | |
| SCHEMBL4163321 | 0.77 | ELANE (0.60) | ELANECTRB1KYNUPRTN3ATM | |
| SCHEMBL8740045 | 0.77 | ELANE (0.60) | ELANECTRB1KYNUPRTN3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |