Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538397 | 0.96 | ABCC4 (0.67) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL28032595 | 0.94 | LMNA (0.63) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL9251496 | 0.89 | ABCC4 (0.74) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL23296113 | 0.87 | GRIN2D (0.57) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL13061620 | 0.86 | BCL2 (0.64) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL27604987 | 0.86 | LMNA (0.68) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL3417462 | 0.85 | GRIN2D (0.59) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL19746447 | 0.85 | GRIN2D (0.55) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL7030142 | 0.85 | ACMSD (0.58) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL17187933 | 0.85 | PLA2G10 (0.60) | ABCC4LMNAGAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300499-B1 | α1-adrenergic receptor antagonists | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-10-09 | — | — | US | disclosed |