Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.62 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.62 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.62 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | RXRA | P19793 | 3/20 | 0.56 |
| ▸ | RXRB | P28702 | 3/20 | 0.56 |
| ▸ | RXRG | P48443 | 3/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032595 | 0.94 | LMNA (0.63) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL538397 | 0.92 | ABCC4 (0.67) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL18427881 | 0.92 | ABCC4 (0.80) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL13061620 | 0.90 | BCL2 (0.64) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL3417462 | 0.89 | GRIN2D (0.59) | ABCC4LMNAGAATSHRPTGS1 | |
| Methyl Alcohol SCHEMBL7855784 | 0.89 | ABCC4 (0.62) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL23296113 | 0.87 | GRIN2D (0.57) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL5269627 | 0.87 | GRIN2D (0.57) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL4213065 | 0.87 | SHMT1 (0.62) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL26084 | 0.86 | LMNA (1.00) | ABCC4LMNAGAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395917-A | Polyester or polyamide copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-07 | — | — | US | disclosed |