Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785647 | 1.00 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL803175 | 0.90 | LMNA (0.39) | SLC6A2SLC6A4SLC6A3KCNH2WDR5 | |
| SCHEMBL785382 | 0.89 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL785381 | 0.89 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL803508 | 0.89 | WDR5 (0.41) | SLC6A2SLC6A4SLC6A3WDR5KMT2A | |
| SCHEMBL484427 | 0.86 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3WDR5KMT2A | |
| SCHEMBL484428 | 0.86 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3WDR5KMT2A | |
| SCHEMBL803189 | 0.85 | TRPM8 (0.43) | SLC6A2SLC6A4SLC6A3WDR5KMT2A | |
| SCHEMBL13131593 | 0.84 | HPGD (0.46) | SLC6A2SLC6A4SLC6A3WDR5KMT2A | |
| SCHEMBL803190 | 0.84 | HPGD (0.46) | SLC6A2SLC6A4SLC6A3WDR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | SLC6A2 1966/4885SLC6A4 1682/4885SLC6A3 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.