Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6075587 | 0.99 | HTR7 (0.40) | HTR7MTNR1ASIGMAR1NQO2MTNR1B | |
| Ammonia Solution, Strong SCHEMBL7857144 | 0.84 | ACHE (0.38) | SIGMAR1ACHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6075590 | 0.82 | ACHE (0.37) | SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL8566958 | 0.80 | MTNR1A (0.41) | MTNR1ASIGMAR1NQO2MTNR1BABCB1 | |
| SCHEMBL8521248 | 0.80 | MTNR1A (0.41) | MTNR1ASIGMAR1NQO2MTNR1BABCB1 | |
| SCHEMBL6076646 | 0.79 | MTNR1A (0.60) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8569498 | 0.78 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1B | |
| SCHEMBL8521850 | 0.78 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1B | |
| SCHEMBL15659806 | 0.77 | ESR1 (0.53) | MTNR1ASIGMAR1NQO2MTNR1B | |
| SCHEMBL7952263 | 0.77 | MTNR1A (0.61) | MTNR1ASIGMAR1NQO2MTNR1BABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077927-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058495-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-11-18 | — | — | WO | disclosed |