Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521248 | 1.00 | MTNR1A (0.41) | MTNR1ASIGMAR1NQO2MTNR1BABCB1 | |
| SCHEMBL8021748 | 0.92 | SIGMAR1 (0.44) | MTNR1ASIGMAR1NQO2MTNR1BABCB1 | |
| SCHEMBL8521850 | 0.81 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1B | |
| SCHEMBL8569498 | 0.81 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1B | |
| SCHEMBL15659806 | 0.81 | ESR1 (0.53) | MTNR1ASIGMAR1NQO2MTNR1B | |
| SCHEMBL7952263 | 0.80 | MTNR1A (0.61) | MTNR1ASIGMAR1NQO2MTNR1BABCB1 | |
| SCHEMBL7857142 | 0.80 | HTR7 (0.40) | MTNR1ASIGMAR1NQO2MTNR1BABCB1 | |
| Hydrochloric Acid SCHEMBL8604303 | 0.80 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1B | |
| Hydrochloric Acid SCHEMBL8604302 | 0.80 | MTNR1A (0.39) | MTNR1ASIGMAR1NQO2MTNR1B | |
| Hydrochloric Acid SCHEMBL15661220 | 0.79 | ESR1 (0.51) | MTNR1ASIGMAR1NQO2MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| US-5780512-A | MELATONINERGIC | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | disclosed |
| US-5693665-A | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-02 | — | — | US | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |