Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858660 | 0.81 | TAS1R3 (0.40) | PTGS2TDP1MIFTAS1R3TAS1R1 | |
| SCHEMBL23493483 | 0.78 | TP53 (0.46) | PTGS2TP53TDP1TRPA1 | |
| SCHEMBL1053847 | 0.76 | ELANE (0.43) | TP53TDP1 | |
| SCHEMBL5942162 | 0.74 | ELANE (0.45) | PTGS2TP53TDP1 | |
| SCHEMBL706769 | 0.73 | ELANE (0.39) | MIF | |
| SCHEMBL23493467 | 0.70 | TP53 (0.44) | PTGS2TP53TDP1TRPA1 | |
| SCHEMBL7864087 | 0.70 | ELANE (0.33) | TP53MIF | |
| SCHEMBL21096985 | 0.68 | TP53 (0.54) | PTGS2TP53TDP1TRPA1 | |
| SCHEMBL23493452 | 0.68 | TP53 (0.42) | PTGS2TP53TDP1TRPA1 | |
| SCHEMBL23493419 | 0.67 | TP53 (0.44) | PTGS2TP53TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |