Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21065536 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL23493457 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL27698650 | 0.72 | ALOX15 (0.44) | ELANEALDH1A1MAPTCYP3A4 | |
| SCHEMBL8086300 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL7858660 | 0.71 | TAS1R3 (0.40) | ELANEALDH1A1MIF | |
| SCHEMBL1053847 | 0.71 | ELANE (0.43) | ELANEALDH1A1TP53GAAMAPT | |
| SCHEMBL7858566 | 0.70 | PTGS2 (0.42) | MIFTP53 | |
| SCHEMBL3372071 | 0.69 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL6564364 | 0.69 | — | — | |
| SCHEMBL6858043 | 0.69 | ALDH1A1 (0.40) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |