Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706767 | 0.84 | HPGD (0.38) | ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL19548017 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TDP1TAS1R3TAS1R1TRPA1 | |
| SCHEMBL7858560 | 0.80 | TP53 (0.41) | ALDH1A1TDP1TRPA1TSHRMEN1 | |
| SCHEMBL475950 | 0.77 | LMNA (0.47) | ALDH1A1TDP1MEN1LMNAMAPT | |
| SCHEMBL25266761 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1TRPA1HDAC8TSHR | |
| SCHEMBL475969 | 0.75 | MAPT (0.43) | ALDH1A1TDP1TSHRKDM4ECYP3A4 | |
| SCHEMBL2770905 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TDP1TAS1R3TAS1R1TRPA1 | |
| SCHEMBL21522355 | 0.74 | LMNA (0.53) | ALDH1A1TDP1TSHRKDM4EMEN1 | |
| SCHEMBL5958178 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TDP1TRPA1HDAC8TSHR | |
| SCHEMBL4874392 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TDP1TRPA1HDAC8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |