SCHEMBL475969

SCHEMBL475969

CC(=O)O[Si](C)(C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ALDH1A1 P00352 4/20 0.41
ESR1 P03372 2/20 0.39
ESR2 Q92731 1/20 0.39
HPGD P15428 3/20 0.38
TSHR P16473 2/20 0.38
NAPRT Q6XQN6 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ELANE P08246 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
HMGB1 P09429 1/20 0.38
GGT1 P19440 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706767 0.89 HPGD (0.38) MAPTALDH1A1HPGDTSHRPOLB
SCHEMBL150540 0.83 MAPT (0.43) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL475923 0.83 MAPT (0.43) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL1719096 0.82 ELANE (0.45) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL475968 0.81 MAPT (0.38) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL475950 0.81 LMNA (0.47) MAPTCES2CES1ALDH1A1HPGD
SCHEMBL10535386 0.81 MAPT (0.38) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL132756 0.80 CES2 (0.43) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL476126 0.80 CES2 (0.43) MAPTCES2CES1ALDH1A1ESR1
SCHEMBL132933 0.80 CES2 (0.43) MAPTCES2CES1ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220280699-A1 NANOCOATINGS AND METHODS FOR FABRICATING AN INTRACARDIAC ECHOCARDIOGRAPHY ULTRASOUND TRANSDUCER ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. 2022-09-08 US claimed
US-10991571-B2 High temperature atomic layer deposition of silicon oxide thin films VERSUM MATERIALS US, LLC (US) 2021-04-27 US claimed
US-20190189431-A1 High Temperature Atomic Layer Deposition of Silicon Oxide Thin Films VERSUM MATERIALS US, LLC (US) 2019-06-20 US claimed
US-20170256399-A9 High Temperature Atomic Layer Deposition Of Silicon Oxide Thin Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-09-07 US claimed
US-20160365244-A1 High Temperature Atomic Layer Deposition Of Silicon Oxide Thin Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-12-15 US claimed
US-20130295779-A1 HIGH TEMPERATURE ATOMIC LAYER DEPOSITION OF SILICON OXIDE THIN FILMS VERSUM MATERIALS US, LLC 2013-11-07 US claimed
EP-2650399-A2 High temperature atomic layer deposition of silicon oxide thin films AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-10-16 EP claimed
US-8039049-B2 Treatment of low dielectric constant films using a batch processing system TOKYO ELECTRON LIMITED (JP) 2011-10-18 US claimed
US-7405168-B2 Plural treatment step process for treating dielectric films TOKYO ELECTRON LIMITED (JP) 2008-07-29 US claimed
US-20080076262-A1 METHOD AND SYSTEM FOR TREATING A DIELECTRIC FILM TOKYO ELECTRON LIMITED (JP) 2008-03-27 US claimed
WO-2006091264-A1 METHOD AND SYSTEM FOR TREATING A DIELECTRIC FILM TOKYO ELECTRON LIMITED (JP) 2006-08-31 WO claimed
US-20050215072-A1 Method and system for treating a dielectric film TOKYO ELECTRON LIMITED (JP) 2005-09-29 US claimed
CN-1630744-A Coated optical fibers using adhesion promoters, and methods for making and using same BORDEN CHEM INC (US) 2005-06-22 CN claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
EP-1432857-A1 COATED OPTICAL FIBERS USING ADHESION PROMOTERS, AND METHODS FOR MAKING AND USING SAME BORDEN CHEMICAL, INC. (US) 2004-06-30 EP claimed
US-20030129397-A1 Coated optical fibers using adhesion promoters, and methods for making and using same HEXION INC. 2003-07-10 US claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
WO-2003023101-A1 COATED OPTICAL FIBERS USING ADHESION PROMOTERS, AND METHODS FOR MAKING AND USING SAME BORDEN CHEMICAL, INC. (US) 2003-03-20 WO claimed
US-4912242-A Process for preparing silicon esters DOW CORNING CORPORATION (US) 1990-03-27 US claimed
US-4208312-A ACYLOXYSILANE COMPONENT TO EXTEND POT LIFE SHIN-ETSU CHEMICAL CO. LTD. (JP) 1980-06-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190189431-A1 High Temperature Atomic Layer Deposition of Silicon Oxide Thin Films VIM, CDH1, ALDOA MAPT 11/4885CES2 2899/4885CES1 3718/4885
US-10991571-B2 High temperature atomic layer deposition of silicon oxide thin films VIM, CDH1, ALDOA MAPT 11/4885CES2 2899/4885CES1 3718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.