SCHEMBL2770905

SCHEMBL2770905

C=Cc1ccc([Si](C)(C)OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TRPA1 O75762 1/20 0.37
TSHR P16473 1/20 0.37
HDAC8 Q9BY41 2/20 0.37
TDP1 Q9NUW8 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
TP53 P04637 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25266761 0.84 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8TDP1
SCHEMBL15469251 0.84 ALDH1A1 (0.41) ALDH1A1TRPA1TSHRHDAC8CHRNB2
SCHEMBL1448787 0.83 ALDH1A1 (0.48) ALDH1A1TRPA1TSHRHDAC8TDP1
SCHEMBL29365084 0.82 CYP1A2 (0.42) ALDH1A1TRPA1TSHRTP53
SCHEMBL5958178 0.81 ALDH1A1 (0.46) ALDH1A1TRPA1TSHRHDAC8TDP1
SCHEMBL676007 0.81 CA12 (0.30)
SCHEMBL5014438 0.80 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8TDP1
SCHEMBL27813923 0.80 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8TDP1
SCHEMBL5012806 0.80 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8TDP1
SCHEMBL100085 0.80 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2821418-B1 HYDROGENATED AROMATIC ALKENYL AND DIENE COPOLYMERS CONTAINING COMONOMERS THAT HAVE SILYL HYDRIDE UNITS AND FUNCTIONALIZED ANALOGUES THEREOF DYNASOL ELASTÓMEROS S A (ES) 2017-03-15 EP claimed
US-9238765-B2 Hydrogenated alkenyl aromatic-diene copolymers containing comonomers having silyl hydride units and their functionalized analogs DYNASOL ELASTOMEROS, S.A. (ES) 2016-01-19 US claimed
US-20150175854-A1 HYDROGENATED ALKENYL AROMATIC-DIENE COPOLYMERS CONTAINING COMONOMERS HAVING SILYL HYDRIDE UNITS AND THEIR FUNCTIONALIZED ANALOGS THE UNIVERSITY OF AKRON (US) 2015-06-25 US claimed
EP-2821418-A1 HYDROGENATED AROMATIC ALKENYL AND DIENE COPOLYMERS CONTAINING COMONOMERS THAT HAVE SILYL HYDRIDE UNITS AND FUNCTIONALIZED ANALOGUES THEREOF Dynasol Elastómeros S.A. (ES) 2015-01-07 EP claimed
US-20050107561-A1 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-05-19 US claimed
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
EP-4570827-A1 CONJUGATED DIENE-BASED POLYMER, MOLDED BODY, PRODUCTION METHOD FOR CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND TIRE Asahi Kasei Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
EP-4134382-B1 HYDROGENATED CONJUGATED DIENE-BASED POLYMER, HYDROGENATED CONJUGATED DIENE-BASED POLYMER COMPOSITION, RUBBER COMPOSITION, AND METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE-BASED POLYMER ASAHI CHEMICAL IND (JP) 2025-05-07 EP disclosed
CN-119497723-A Conjugated diene polymer, molded article, method for producing conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2025-02-21 CN disclosed
CN-119462990-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2025-02-18 CN disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
US-12215179-B2 Conjugated diene-based polymer, branching agent, production method for conjugated diene-based polymer, oil extended conjugated diene-based polymer, rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-04 US disclosed
EP-0505997-A2 Process for producing styrenic polymer and copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
US-5115034-A Branching polymers with organometallic styrene derivative, a hydrocarbyl lithium initiator and a monomer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-05-19 US disclosed
US-5079090-A Pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-07 US disclosed
US-4996266-A Branched elastomeric and block copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-26 US disclosed
US-4957808-A POROUS SUPPROT LAMINATED WITH PLASTIC FILM RICOH COMPANY, LTD. (JP) 1990-09-18 US disclosed
US-4906691-A Adhesive compositions made with condensed phase polymers and sheet materials coated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-06 US disclosed
US-4857618-A ELASTOMERIC, ANIONIC COPOLYMERS; ORGANOMETALLIC CONDENSING AGENT; PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed
US-4857615-A Method of making condensed phase polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 ALDH1A1 2948/4885TRPA1 3887/4885TSHR 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.