Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 14/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7859146 | 0.94 | LNPEP (0.48) | LNPEPERAP2ERAP1LTA4HMETAP2 | |
| SCHEMBL7860762 | 0.91 | LNPEP (0.47) | LNPEPERAP2ERAP1ITGB3ITGA2B | |
| SCHEMBL8362723 | 0.89 | LNPEP (0.46) | LNPEPERAP2ERAP1METAP2 | |
| SCHEMBL7860804 | 0.89 | MMP2 (0.47) | LTA4HITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7860829 | 0.86 | LNPEP (0.44) | LNPEPERAP2ERAP1ITGB3ITGA2B | |
| SCHEMBL7850357 | 0.86 | MMP2 (0.51) | LNPEPERAP2ERAP1LTA4HITGB3 | |
| SCHEMBL8362562 | 0.85 | LNPEP (0.43) | LNPEPERAP2ERAP1METAP2 | |
| Trifluoroacetic Acid SCHEMBL7860786 | 0.84 | KDM4E (0.43) | LTA4HITGB3ITGA2B | |
| SCHEMBL7850353 | 0.78 | LTA4H (0.50) | LNPEPERAP2ERAP1LTA4HMETAP2 | |
| SCHEMBL7857783 | 0.78 | LNPEP (0.43) | LNPEPERAP2ERAP1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |