Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850357 | 0.97 | MMP2 (0.51) | MMP2LTA4HITGB3ITGA2BPPARG | |
| Trifluoroacetic Acid SCHEMBL7860786 | 0.95 | KDM4E (0.43) | MMP2LTA4HFCER2ITGB3ITGA2B | |
| SCHEMBL7860762 | 0.92 | LNPEP (0.47) | MMP2FCER2ITGB3ITGA2BPPARG | |
| SCHEMBL7859103 | 0.89 | LNPEP (0.52) | LTA4HITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7860829 | 0.87 | LNPEP (0.44) | FCER2ITGB3ITGA2BPPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL7859146 | 0.86 | LNPEP (0.48) | LTA4HITGB3ITGA2B | |
| SCHEMBL7860823 | 0.83 | MMP2 (0.44) | MMP2LTA4HHDAC3HDAC4HDAC1 | |
| SCHEMBL7857072 | 0.82 | MMP2 (0.47) | MMP2LTA4HFCER2ITGB3ITGA2B | |
| SCHEMBL7860801 | 0.82 | LTA4H (0.51) | MMP2LTA4HFCER2HDAC3HDAC4 | |
| SCHEMBL7857783 | 0.81 | LNPEP (0.43) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |