Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857074 | 0.82 | ADAMTS4 (0.38) | LNPEPERAP2LTA4HDPP4DPP8 | |
| SCHEMBL7860804 | 0.81 | MMP2 (0.47) | LTA4H | |
| SCHEMBL7850357 | 0.78 | MMP2 (0.51) | LNPEPERAP2LTA4HERAP1 | |
| SCHEMBL7859103 | 0.78 | LNPEP (0.52) | LNPEPERAP2LTA4HERAP1 | |
| Trifluoroacetic Acid SCHEMBL7860786 | 0.77 | KDM4E (0.43) | KMT2ALTA4H | |
| SCHEMBL27518599 | 0.77 | METAP2 (0.55) | POLBKMT2ATDP1 | |
| SCHEMBL27518604 | 0.77 | METAP2 (0.55) | POLBKMT2ATDP1 | |
| SCHEMBL7860762 | 0.77 | LNPEP (0.47) | LNPEPERAP2ERAP1 | |
| SCHEMBL7024530 | 0.74 | METAP2 (0.54) | KMT2ALTA4HTDP1DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL7859146 | 0.74 | LNPEP (0.48) | LNPEPERAP2LTA4HERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |