SCHEMBL785931

SCHEMBL785931

CCOC(C)OC(=O)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
PRKCA P17252 1/20 0.41
MMP8 P22894 1/20 0.34
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18651087 0.87 PRKCA (0.40) LMNAPRKCAMMP8
SCHEMBL47442 0.83 LMNA (0.42) LMNAMMP8
SCHEMBL10068115 0.83 LMNA (0.42) LMNAMMP8
SCHEMBL10098354 0.83 LMNA (0.42) LMNAMMP8
SCHEMBL786188 0.82 LMNA (0.41) LMNAMMP8
SCHEMBL8211801 0.81 PRKCA (0.45) PRKCA
SCHEMBL10693911 0.81 LMNA (0.44) LMNAMMP8
SCHEMBL25883981 0.80 LMNA (0.39) LMNAMMP8
SCHEMBL247190 0.80 PRKCA (0.37) LMNAPRKCA
SCHEMBL14679311 0.78 ALDH1A1 (0.44) LMNAPRKCAMMP8THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120071638-A1 Copolymer for positive type lithography, polymerization initiator used in production of said copolymer, and composition for semiconductor lithography MARUZEN PETROCHEMICAL CO., LTD. (JP) 2012-03-22 US disclosed
US-8067516-B2 Copolymer for positive type lithography, polymerization initiator used in production of said copolymer, and composition for semiconductor lithography MARUZEN PETROCHEMICAL CO., LTD. (JP) 2011-11-29 US disclosed
US-20100152418-A1 Switch-Peptides as Tool for the Study of Fibrillogenesis EPFL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) 2010-06-17 US disclosed
US-20070269741-A1 Copolymer for positive type lithography, polymerization initiator used in production of said copolymer, and composition for semiconductor lithography MARUZEN PETROCHEMICAL CO., LTD. (JP) 2007-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071638-A1 Copolymer for positive type lithography, polymerization initiator used in production of said copolymer, and composition for semiconductor lithography FRG1, H1-10, POLL LMNA 1014/4885PRKCA 1199/4885MMP8 4339/4885
US-20100152418-A1 Switch-Peptides as Tool for the Study of Fibrillogenesis IAPP, APP, SPPL2B LMNA 134/4885PRKCA 3031/4885MMP8 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.