Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19965585 | 0.90 | POLB (0.31) | POLBMAPT | |
| SCHEMBL14265654 | 0.78 | MAPT (0.31) | POLBMAPT | |
| SCHEMBL22578076 | 0.77 | — | — | |
| SCHEMBL26983602 | 0.76 | PTPN1 (0.31) | — | |
| SCHEMBL9981990 | 0.76 | METAP2 (0.30) | — | |
| SCHEMBL25213730 | 0.75 | — | — | |
| SCHEMBL17621259 | 0.73 | ALDH1A1 (0.30) | KMT2A | |
| SCHEMBL1057403 | 0.73 | L3MBTL1 (0.32) | POLB | |
| SCHEMBL14498503 | 0.72 | POLB (0.30) | POLBMAPT | |
| SCHEMBL46361 | 0.72 | KMT2A (0.34) | POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615848-A1 | COMPOUNDS AND COMPOSITIONS AS EIF4E INHIBITORS AND USES THEREOF | Ribometrix, Inc. (US) | 2025-09-17 | — | — | EP | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2024238406-A1 | FUROPYRIDINE COMPOUNDS AS P53 MUTANT STABILIZER AND USES THEREOF | FRONTIER MEDICINES CORPORATION (US) | 2024-11-21 | — | — | WO | disclosed |
| US-20240246979-A1 | cGAS INHIBITORS | ELI LILLY AND COMPANY | 2024-07-25 | — | — | US | disclosed |
| US-20240246918-A1 | COMPOUNDS AND COMPOSITIONS AS EIF4E INHIBITORS AND THE USES THEREOF | RIBOMETRIX, INC. | 2024-07-25 | — | — | US | disclosed |
| WO-2024137752-A1 | AZEPINO[4,5-B]INDOLONE CGAS INHIBITORS | ELI LILLY AND COMPANY (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024103069-A1 | COMPOUNDS AND COMPOSITIONS AS eIF4E INHIBITORS AND USES THEREOF | RIBOMETRIX, INC. (US) | 2024-05-16 | — | — | WO | disclosed |
| US-20240000119-A1 | MEGASTIGMANE DERIVATIVE COMPOSITIONS AND METHODS FOR TASTE MODULATION | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2024-01-04 | — | — | US | disclosed |
| CN-110582485-B | Pyrazole derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2023-10-13 | — | — | CN | disclosed |
| EP-4250958-A1 | MEGASTIGMANE DERIVATIVE COMPOSITIONS AND METHODS FOR TASTE MODULATION | International Flavors & Fragrances Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| US-7235698-B2 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-26 | — | — | US | disclosed |
| WO-2006102097-A2 | SYNTHESIS OF AVRAINVILLAMIDE, STEPHACIDIN B, AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-09-28 | — | — | WO | disclosed |
| US-7067527-B2 | Thienopyridine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1259515-B1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | TAKEDA PHARMACEUTICAL (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20040054183-A1 | Thienopyridine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| US-6653476-B2 | Antiinflammatory and antiarthritic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-25 | — | — | US | disclosed |
| US-20030130517-A1 | Thienopyridine derivatives , their production and use | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1259515-A2 | THIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001064685-A2 | THIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-09-07 | — | — | WO | disclosed |
| US-5547960-A | ACETYLCHOLINESTERASE INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1996-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130517-A1 | Thienopyridine derivatives , their production and use | ALK, HRH2, TBXA2R | POLB 2530/4885MAPT 3749/4885KMT2A 866/4885 |
| US-20240246918-A1 | COMPOUNDS AND COMPOSITIONS AS EIF4E INHIBITORS AND THE USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | POLB 1373/4885MAPT 1449/4885KMT2A 2630/4885 |
| US-20240246979-A1 | cGAS INHIBITORS | CGAS, STING1, IRF3 | POLB 282/4885MAPT 1847/4885KMT2A 4033/4885 |
| US-20040054183-A1 | Thienopyridine derivatives, their production and use | ALK, HRH2, TBXA2R | POLB 2530/4885MAPT 3749/4885KMT2A 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.