SCHEMBL26983602

SCHEMBL26983602

CC1(C(=O)O)CC2(CCC1=O)OCCO2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.31
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31012850 0.82 SMN1; SMN2 (0.35)
SCHEMBL16370866 0.79 CYP2C19 (0.39) PTPN1
SCHEMBL785938 0.76 POLB (0.33)
SCHEMBL16460776 0.76 FFAR3 (0.36) FFAR3
SCHEMBL9981990 0.72 METAP2 (0.30)
SCHEMBL20535917 0.72 PTPN1 (0.33) PTPN1
SCHEMBL20535913 0.72 PTPN1 (0.33) PTPN1
SCHEMBL19965585 0.71 POLB (0.31)
SCHEMBL22578076 0.70
SCHEMBL10257396 0.69 CYP1A2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11987577-B2 Therapeutic compounds and methods ACTIO BIOSCIENCES, INC. (US) 2024-05-21 US disclosed
US-20240076294-A1 THERAPEUTIC COMPOUNDS AND METHODS ACTIO BIOSCIENCES, INC. 2024-03-07 US disclosed
WO-2024011214-A1 THERAPEUTIC COMPOUNDS AND METHODS ACTIO BIOSCIENCES, INC. (US) 2024-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11987577-B2 Therapeutic compounds and methods TRPV4, TRPV3, TRPV2 PTPN1 3178/4885FFAR3 392/4885
US-20240076294-A1 THERAPEUTIC COMPOUNDS AND METHODS TRPV4, TRPV3, TRPV2 PTPN1 3178/4885FFAR3 392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.