Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858587 | 0.87 | UCHL1 (0.33) | ABCB1 | |
| SCHEMBL7859559 | 0.85 | ABCB1 (0.35) | ABCB1MAPTNPSR1SIRT2GPR119 | |
| SCHEMBL7858621 | 0.82 | PARP1 (0.31) | ABCB1 | |
| SCHEMBL9096789 | 0.80 | PARP1 (0.35) | — | |
| SCHEMBL7852779 | 0.79 | KLK7 (0.33) | ABCB1GPR119 | |
| SCHEMBL7854724 | 0.76 | ABCB1 (0.34) | ABCB1MAPTNPSR1 | |
| SCHEMBL7853709 | 0.76 | ABCB1 (0.40) | ABCB1MAPTNPSR1SIRT2 | |
| SCHEMBL7860702 | 0.76 | NR1H3 (0.36) | ABCB1GPR119 | |
| SCHEMBL7858617 | 0.74 | — | — | |
| SCHEMBL7860696 | 0.73 | KLK7 (0.37) | ABCB1MAPTNPSR1SIRT2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |