Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868237 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL868238 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL867813 | 0.91 | LMNA (0.43) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL7856855 | 0.91 | LMNA (0.43) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL867814 | 0.91 | LMNA (0.43) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL868448 | 0.89 | GHSR (0.42) | GHSROPRD1 | |
| SCHEMBL4372111 | 0.89 | GHSR (0.42) | GHSROPRD1 | |
| SCHEMBL4372106 | 0.89 | GHSR (0.42) | GHSROPRD1 | |
| SCHEMBL4382952 | 0.89 | OPRD1 (0.38) | MEN1KMT2ANPC1RAB9AGHSR | |
| SCHEMBL866628 | 0.89 | GHSR (0.51) | MEN1KMT2AALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077941-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | Novo Nordisk A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058501-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |