Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 6/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375272 | 0.91 | GHSR (0.35) | OPRD1GHSRDPP4MEN1KMT2A | |
| SCHEMBL4385374 | 0.90 | GHSR (0.40) | OPRD1GHSRDPP4 | |
| SCHEMBL4369742 | 0.89 | GHSR (0.48) | OPRD1GHSRDPP4MEN1KMT2A | |
| SCHEMBL868238 | 0.89 | MEN1 (0.43) | OPRD1GHSRMEN1KMT2ANPC1 | |
| SCHEMBL868237 | 0.89 | MEN1 (0.43) | OPRD1GHSRMEN1KMT2ANPC1 | |
| SCHEMBL7860577 | 0.89 | MEN1 (0.43) | OPRD1GHSRMEN1KMT2ANPC1 | |
| SCHEMBL4372106 | 0.83 | GHSR (0.42) | OPRD1GHSRDPP4 | |
| SCHEMBL868448 | 0.83 | GHSR (0.42) | OPRD1GHSRDPP4 | |
| SCHEMBL4372111 | 0.83 | GHSR (0.42) | OPRD1GHSRDPP4 | |
| SCHEMBL4369760 | 0.80 | GHSR (0.48) | GHSRDPP4P2RX7ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077941-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2009-08-12 | — | — | EP | claimed |