Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861001 | 0.90 | NPC1 (0.35) | CYP19A1CYP11B1CYP11B2LTA4HMAPK14 | |
| SCHEMBL7859923 | 0.79 | CYP19A1 (0.36) | CYP19A1CYP11B1CYP11B2LTA4HMAPK14 | |
| SCHEMBL7861309 | 0.79 | HTR6 (0.40) | NPC1RAB9AALDH1A1 | |
| SCHEMBL7861310 | 0.75 | MAPT (0.44) | CYP19A1CYP11B1CYP11B2CNR1ACHE | |
| SCHEMBL7859944 | 0.72 | HTR1A (0.41) | LTA4HMAPK14NPC1RAB9ALIPE | |
| SCHEMBL7854338 | 0.72 | HTR1A (0.36) | LTA4HMAPK14RAB9AMAOBGAA | |
| SCHEMBL7859937 | 0.71 | LMNA (0.40) | MAOBALDH1A1GAA | |
| SCHEMBL7859925 | 0.71 | HTR1A (0.46) | LIPEALDH1A1GAA | |
| SCHEMBL7861125 | 0.69 | MEN1 (0.39) | NPC1RAB9AALDH1A1GAA | |
| SCHEMBL9252950 | 0.67 | CHRNB2 (0.40) | NPC1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | claimed |
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | disclosed |