Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778615 | 0.93 | HIF1A (0.39) | HIF1AL3MBTL1MEN1KMT2ANLRP3 | |
| SCHEMBL29778327 | 0.78 | NPC1 (0.46) | HIF1AMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6811343 | 0.78 | NPC1 (0.46) | HIF1AMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6811346 | 0.78 | NPC1 (0.46) | HIF1AMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7575928 | 0.74 | VNN1 (0.37) | HIF1AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL7784341 | 0.73 | MAPT (0.49) | L3MBTL1LMNAMAPTRAB9ANPC1 | |
| SCHEMBL7571037 | 0.73 | HIF1A (0.35) | HIF1AL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7782583 | 0.72 | RAB9A (0.39) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7785594 | 0.69 | L3MBTL1 (0.46) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7846221 | 0.69 | KMT2A (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |