Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | EEF2K | O00418 | 2/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862023 | 0.83 | CA2 (0.39) | CA2CA12CA1CA4CA9 | |
| SCHEMBL7866927 | 0.80 | FFAR1 (0.45) | ITGB3ITGAV | |
| SCHEMBL7863123 | 0.77 | ITGB3 (0.39) | CA2CA12CA1CA4CA9 | |
| SCHEMBL7864160 | 0.76 | FFAR1 (0.39) | ITGB3ITGAVCTSA | |
| SCHEMBL7856436 | 0.75 | ITGB3 (0.48) | ITGB3 | |
| SCHEMBL7866947 | 0.75 | PTPN11 (0.41) | EEF2KCTSA | |
| SCHEMBL7457204 | 0.73 | ITGB3 (0.53) | ITGB3 | |
| SCHEMBL7866912 | 0.73 | SMN1; SMN2 (0.41) | ITGB3ITGAVEEF2KCTSA | |
| SCHEMBL7864176 | 0.72 | CTSA (0.34) | ITGB3CTSA | |
| SCHEMBL7861983 | 0.71 | CTSA (0.33) | CA2CA12CA1CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |