Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 9/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864160 | 0.73 | FFAR1 (0.39) | CTSACYP2C19TACR1ITGB3ITGA2B | |
| SCHEMBL7862026 | 0.72 | CA2 (0.36) | CTSAITGB3 | |
| SCHEMBL7866947 | 0.72 | PTPN11 (0.41) | CTSACYP2C19 | |
| SCHEMBL7866927 | 0.70 | FFAR1 (0.45) | TACR1ITGB3 | |
| SCHEMBL7457204 | 0.70 | ITGB3 (0.53) | HPGDITGB3ITGA2B | |
| SCHEMBL7856436 | 0.70 | ITGB3 (0.48) | MAPTITGB3ITGA2B | |
| SCHEMBL7863123 | 0.70 | ITGB3 (0.39) | CTSAMAPTITGB3 | |
| SCHEMBL7864766 | 0.68 | ITGB3 (0.38) | CTSACYP2C19CYP3A4MAPTCYP2C9 | |
| SCHEMBL7863159 | 0.68 | KMT2A (0.56) | CTSA | |
| SCHEMBL8501227 | 0.68 | ITGB3 (0.40) | CTSAITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | disclosed |