Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | HPN | P05981 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862026 | 0.83 | CA2 (0.36) | CA2ITGB3SCN3ACA12CA1 | |
| SCHEMBL7862046 | 0.79 | ITGB3 (0.45) | CA2ITGB3CA1POLBMAPT | |
| SCHEMBL7862025 | 0.78 | TSHR (0.52) | HTTPOLBMAPTALDH1A1LMNA | |
| SCHEMBL7863273 | 0.78 | FFAR1 (0.43) | ITGB3ITGA2BPOLBMAPTLMNA | |
| SCHEMBL7856539 | 0.77 | ITGB3 (0.41) | CA2ITGB3CA12CA1CA9 | |
| SCHEMBL7856433 | 0.76 | ITGB3 (0.54) | ITGB3ITGA2BHTTPLAUPOLB | |
| SCHEMBL7455765 | 0.75 | ITGB3 (0.58) | ITGB3ITGA2BPLAUPOLBALDH1A1 | |
| SCHEMBL7863285 | 0.74 | ITGB3 (0.48) | ITGB3ITGA2BPOLBMAPTALDH1A1 | |
| SCHEMBL7861944 | 0.73 | HDAC1 (0.45) | ITGB3ITGA2BPOLBMAPTALDH1A1 | |
| SCHEMBL7856431 | 0.73 | HDAC1 (0.45) | ITGB3ITGA2BPOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |