Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867901 | 0.93 | EGFR (0.39) | MEN1KMT2AEGFRP4HTMEPHX2 | |
| SCHEMBL7862728 | 0.92 | MEN1 (0.39) | MEN1KMT2AEGFRP4HTMALDH1A1 | |
| SCHEMBL9574695 | 0.92 | CA2 (0.48) | MEN1KMT2AEGFRP4HTMALDH1A1 | |
| SCHEMBL7862835 | 0.92 | EGFR (0.41) | MEN1KMT2AEGFRP4HTMEPHX2 | |
| SCHEMBL7862841 | 0.91 | CA1 (0.40) | MEN1KMT2AP4HTMALDH1A1EPHX2 | |
| SCHEMBL7870515 | 0.90 | POLB (0.44) | MEN1KMT2AEGFRP4HTMALDH1A1 | |
| SCHEMBL9018021 | 0.90 | P4HTM (0.44) | MEN1KMT2AEGFRP4HTMALDH1A1 | |
| SCHEMBL7874550 | 0.88 | ALDH1A1 (0.44) | MEN1KMT2AEGFRP4HTMALDH1A1 | |
| SCHEMBL7870523 | 0.88 | MEN1 (0.47) | MEN1KMT2AP4HTMALDH1A1OPRM1 | |
| SCHEMBL8870118 | 0.87 | P4HTM (0.48) | MEN1KMT2AEGFRP4HTMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |