Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871670 | 0.93 | CA1 (0.41) | CA1CA2OPRM1OPRD1RAB9A | |
| SCHEMBL7871648 | 0.91 | RAB9A (0.39) | CA1CA2OPRM1OPRD1RAB9A | |
| SCHEMBL7862691 | 0.91 | MEN1 (0.41) | CA1CA2OPRM1OPRD1CA7 | |
| SCHEMBL9018117 | 0.91 | OPRM1 (0.40) | CA1CA2OPRM1OPRD1RAB9A | |
| SCHEMBL7862676 | 0.89 | RAB9A (0.46) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9574748 | 0.88 | RAB9A (0.41) | CA1CA2OPRM1OPRD1RAB9A | |
| SCHEMBL7874604 | 0.88 | RAB9A (0.44) | CA1CA2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9574662 | 0.88 | CA1 (0.40) | CA1CA2OPRM1OPRD1RAB9A | |
| SCHEMBL7869478 | 0.88 | KDM4E (0.44) | OPRM1OPRD1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7870558 | 0.88 | PPARA (0.46) | CA1CA2RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |