Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.54 |
| ▸ | PPARG | P37231 | 12/20 | 0.54 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864776 | 0.90 | PPARG (0.53) | EPHX2PPARGPPARAPPARDLMNA | |
| SCHEMBL7864170 | 0.87 | EPHX2 (0.47) | EPHX2PPARGLMNABCHE | |
| SCHEMBL7862050 | 0.83 | PPARG (0.44) | EPHX2PPARGLMNABCHE | |
| SCHEMBL7864267 | 0.82 | TP53 (0.45) | PPARGLMNABCHE | |
| SCHEMBL7856477 | 0.81 | TP53 (0.41) | LMNABCHE | |
| SCHEMBL7856483 | 0.80 | SIRT2 (0.48) | EPHX2PPARGLMNA | |
| SCHEMBL7864706 | 0.79 | MMP13 (0.48) | LMNABCHE | |
| SCHEMBL7862001 | 0.79 | ITGB3 (0.48) | LMNABCHE | |
| SCHEMBL7861998 | 0.79 | ITGB3 (0.48) | LMNABCHE | |
| SCHEMBL7864788 | 0.78 | SIRT2 (0.44) | EPHX2PPARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | disclosed |