Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 13/20 | 0.50 |
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863145 | 0.90 | EPHX2 (0.54) | PPARGEPHX2PPARAPPARDLMNA | |
| SCHEMBL7864267 | 0.88 | TP53 (0.45) | PPARGLMNABCHE | |
| SCHEMBL7862001 | 0.85 | ITGB3 (0.48) | LMNABCHE | |
| SCHEMBL7861998 | 0.85 | ITGB3 (0.48) | LMNABCHE | |
| SCHEMBL7864788 | 0.84 | SIRT2 (0.44) | PPARGEPHX2LMNA | |
| SCHEMBL7856483 | 0.84 | SIRT2 (0.48) | PPARGEPHX2LMNA | |
| SCHEMBL7457847 | 0.84 | MEN1 (0.51) | PPARGLMNA | |
| SCHEMBL7377643 | 0.83 | F10 (0.46) | PPARGEPHX2LMNA | |
| SCHEMBL7864170 | 0.82 | EPHX2 (0.47) | PPARGEPHX2LMNABCHE | |
| SCHEMBL7864751 | 0.82 | SIRT2 (0.41) | PPARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |