Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | AKT2 | P31751 | 2/20 | 0.32 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720305 | 0.83 | FGFR1 (0.42) | FGFR1FGFR4LMNASMN1; SMN2AKT1 | |
| SCHEMBL7869023 | 0.76 | PRPS1 (0.51) | MAPTHSD17B10LMNAALOX15TSHR | |
| SCHEMBL4232433 | 0.75 | MEN1 (0.46) | MAPTHSD17B10LMNAALOX15TSHR | |
| SCHEMBL30168571 | 0.73 | DYRK1A (0.50) | FGFR1FGFR4DYRK1ADPP4DPP8 | |
| SCHEMBL6770226 | 0.73 | DYRK1A (0.50) | FGFR1FGFR4DYRK1ADPP4DPP8 | |
| SCHEMBL18226830 | 0.71 | GABRG2 (0.41) | FGFR1FGFR4LMNATSHRMAPK13 | |
| SCHEMBL6176928 | 0.70 | ADORA2A (0.44) | FGFR1FGFR4MAPTLMNASMN1; SMN2 | |
| SCHEMBL8088090 | 0.70 | MAPT (0.56) | FGFR1MAPTHSD17B10LMNAALOX15 | |
| SCHEMBL6209132 | 0.70 | ADORA2A (0.44) | FGFR1FGFR4MAPTLMNASMN1; SMN2 | |
| SCHEMBL8088086 | 0.69 | FDPS (0.48) | MAPTHSD17B10LMNATSHRMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313101-B1 | ANTIBIOTICS | AVENTIS PHARMA S.A. (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1026170-A1 | Erythromycin derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 2000-08-09 | — | — | EP | disclosed |