Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2944448 | 0.82 | ALDH1A1 (0.34) | ALDH1A1KDM4EMEN1LMNAMAPT | |
| SCHEMBL9402759 | 0.76 | ALDH1A1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL812109 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL28273783 | 0.73 | CYP3A4 (0.37) | ELANEALDH1A1USP2KDM4EMEN1 | |
| SCHEMBL9402643 | 0.73 | TSHR (0.37) | ALDH1A1LMNAKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL1397183 | 0.72 | ALOX15 (0.44) | ELANEALDH1A1USP2KDM4EMEN1 | |
| SCHEMBL143427 | 0.72 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL7858657 | 0.71 | TAS1R3 (0.38) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1053845 | 0.71 | ELANE (0.43) | ELANEALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL9615715 | 0.70 | ALDH1A1 (0.40) | ELANEALDH1A1USP2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |