Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908502 | 0.84 | PLA2G1B (0.37) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7638276 | 0.83 | MEN1 (0.50) | MAPTMAPK1ALDH1A1CYP19A1MEN1 | |
| SCHEMBL7981937 | 0.81 | MAOA (0.54) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7644918 | 0.81 | QPCT (0.45) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7914787 | 0.81 | MYC (0.48) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7162135 | 0.80 | IDO1 (0.47) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7641142 | 0.78 | NPC1 (0.58) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7639607 | 0.75 | TRPV1 (0.46) | — | |
| SCHEMBL7161939 | 0.70 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7644626 | 0.70 | DRD2 (0.43) | MAPTMAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |