Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.49 |
| ▸ | ITGAV | P06756 | 3/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864224 | 0.96 | NAMPT (0.51) | NAMPTITGB3ITGAVGHSRCA12 | |
| SCHEMBL7856493 | 0.85 | NAMPT (0.53) | NAMPTITGB3ITGAVGHSRMAPT | |
| SCHEMBL7861846 | 0.85 | CA1 (0.44) | GHSRCA12CA1CA2CA9 | |
| SCHEMBL7861976 | 0.83 | CA12 (0.43) | GHSRCA12CA1CA2CA9 | |
| SCHEMBL7864272 | 0.82 | NAMPT (0.58) | NAMPTITGB3ITGAVGHSRCA12 | |
| SCHEMBL7864723 | 0.81 | TGFBR1 (0.38) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL7856514 | 0.79 | ITGB3 (0.64) | NAMPTITGB3ITGAVGHSRCA12 | |
| SCHEMBL7864643 | 0.78 | ALDH1A1 (0.39) | GHSRCA12CA1CA2CA9 | |
| SCHEMBL7863252 | 0.74 | ITGB3 (0.58) | NAMPTITGB3ITGAVGHSRCA12 | |
| SCHEMBL20671545 | 0.73 | CA12 (0.55) | GHSRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |